Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Back pain and stiffness plaquenil Chloroquine high creatinine Baseline reading for plaquenil therapy Chloroquine is an inexpensive antimalarial used for several decades and marketed in particular under the name of Nivaquine. This treatment is often recommended when planning to go to an area infested with the malaria parasite, transmitted by mosquitoes. Malaria Information and Prophylaxis by Country; Country Areas with Malaria Drug Resistance 2 Malaria Species 3 Recommended Chemoprophylaxis 4 Key Information Needed and Helpful Links to Assess Need for Prophylaxis for Select Countries; Democratic Republic of the Congo Congo-Kinshasa All Chloroquine P. falciparum 90%, P. ovale 5%, P. vivax rare Chloroquine-resistant malaria is exactly what it sounds like—particular types of malaria which are not cured by treatment with chloroquine. Chloroquine was first discovered in the 1930s in Germany and began to be widely used as an anti-malaria post-World War II, in the late 1940s. Chloroquine is also used to treat amebiasis (infection caused by amoebae). Chloroquine is used to treat and to prevent malaria. Malaria resistance to chloroquine Chloroquine resistance – Malaria Site, CDC - Malaria - Travelers - Malaria Information and. Plaquenil and visual field testingPlaquenil maculopathy reportIs plaquenil a high risk medication CDC has no limits on the use of chloroquine for the prevention of malaria. Medicines for the Prevention of Malaria While Traveling.. Chloroquine Resistant Malaria –. Chloroquine Resistance in Plasmodium falciparum - microbewiki. Chloroquine, an antimalaria drug of the group of 4-aminoquinolines, works well and effectively as a schizonticidal drug against the erythrocytic forms of all types of plasmodia. Today though, almost all pathogens of the potentially lethal malaria tropica have become resistant to this rather well tolerated, and for many decades, useful medication. In P. falciparum the cause of the most lethal human malaria, chloroquine resistance is linked to multiple mutations in PfCRT, a protein that likely functions as a transporter in the parasite’s digestive vacuole membrane. Rapid diagnostic assays for PfCRT mutations are already employed as surveillance tools for drug resistance. The malaria parasite's development of resistance to the drug chloroquine is a major threat to world health. A protein likely to be involved in chloroquine resistance has recently been identified; this discovery is important, but raises as many questions as it answers.