Regardless of the problem, we'd like to help you find what you're looking for. Compared to healthy rats (left), rats with the Charcot-Marie-Tooth disease (central) show less myelin surrounding the axons, visible as missing blue rings. Plaquenil toxicity screening recommendations Hydroxychloroquine pn singlecare Charcot-Marie-Tooth disease CMT is one of the most common inherited neurological disorders, affecting approximately 1 in 2,500 people in the United States. The disease is named for the three physicians who first identified it in 1886 -- Jean-Martin Charcot and Pierre Marie in Paris, France, and Howard Henry Tooth in Cambridge, England. Charcot-Marie-Tooth CMT disease is an inherited disorder of the peripheral nerves. CMT and other inherited disorders are due to defects of genes for various proteins in the nerve fibers. The inheritance pattern in these disorders can be autosomal dominant, autosomal recessive or X-linked. The symptoms of Charcot-Marie-Tooth disease CMT can differ from person to person, even among relatives with the condition. Symptoms can vary depending on the type of CMT, and even people with the same type can experience it differently. For example, it's not possible to predict the age at which symptoms will first appear, how quickly the condition will progress, or its severity. Read about the causes of CMT for more information on the different types. Credit: Max-Planck-Institute for Experimental Medicine Charcot-Marie-Tooth disease is the most common hereditary neuropathy and affects more than 2 million people worldwide. Animals treated with Lecithin (right) show an increase in myelinated filaments. Hydroxychloroquine and charcot marie tooth disease Charcot-Marie Tooth Disease Foot Deformities - FootEducation, Charcot-Marie-Tooth Disease - Johns Hopkins Hospital Plaquenil and neuropathyHydroxychloroquine side effects rash pictures Charcot shahr-KOH-Marie-Tooth disease is a group of inherited disorders that cause nerve damage. This damage is mostly in your arms and legs peripheral nerves. Charcot-Marie-Tooth disease is also called hereditary motor and sensory neuropathy. Charcot-Marie-Tooth disease results in smaller, weaker muscles. Charcot-Marie-Tooth disease - Symptoms and causes - Mayo.. Charcot-Marie-Tooth disease - Symptoms - NHS. Charcot-Marie-Tooth disease type 1 Genetic and Rare.. Charcot–Marie–Tooth disease CMT is one of the hereditary motor and sensory neuropathies of the peripheral nervous system characterized by progressive loss of muscle tissue and touch sensation across various parts of the body. Charcot-Marie-Tooth Disease affects the nerves outside the spinal cord and brain. People with the condition can have problems with their feet and trouble balancing. Three doctors -- Jean-Martin Charcot, Pierre Marie and Howard Henry Tooth – identified a nerve disease back in 1886. Today, a whole group of genetic disorders is named after that trio. There's no cure for Charcot-Marie-Tooth disease. But the disease generally progresses slowly, and it doesn't affect expected life span. There are some treatments to help you manage Charcot-Marie-Tooth disease. Medications. Charcot-Marie-Tooth disease may sometimes cause pain due to muscle cramps or nerve damage.