Chloroquine phosphate, 250 mg twice daily, or hydroxychloroquine sulfate, 200 mg twice daily, was administered for a period of 6 to 21 months. Patients had regular clinical evaluation, determination of serum and cerebrospinal fluid angiotensin-converting enzyme level, computed tomography or magnetic resonance imaging, chest radiography, lung function testing, and slit-lamp examination of the eyes. What times do i take hydroxychloroquine Hydroxychloroquine sulfate tablets side effects Plaquenil side effects sunlight With regard to plaquenil and Eye tests, the eye issues produced by sarcoidosis such as uveitis are quite different from the potential for retinal toxicity which can occur with Plaquenil. The tests are Field Tests for peripheral vision. Retinal toxicity of plaquenil can cause tunnel vision. This is why the eye tests are performed. Sarcoidosis in children is frequently of extrapulmonary type with frequent ocular as well as cutaneous and rheumatological manifestations and has a guarded prognosis.37 38 The triad—rash, uveitis, and arthritis—is characteristic for children under 4 years of age; more frequent is the occurrence of sarcoidosis in older children 8–15 years of age, which is characterised by almost universal lung involvement and manifestations in eyes, skin, liver, and spleen. Hydroxychloroquine Plaquenil may be helpful for skin lesions and elevated blood-calcium levels. Tumor necrosis factor-alpha TNF-alpha inhibitors. These medications are commonly used to treat the inflammation associated with rheumatoid arthritis. They can also be helpful in treating sarcoidosis that hasn't responded to other treatments. Magnetic resonance imaging with gadolinium was most helpful in supporting the diagnosis of sarcoidosis and monitoring the course of the disease. Chloroquine or hydroxychloroquine either stabilized symptoms or controlled neurological symptoms in 10 of 12 patients. Cerebrospinal fluid abnormalities, including lymphocytosis, were seen in 3 patients. Plaquenil sarcoidosis uveitis Nonsteroidal therapy of sarcoidosis, Ocular involvement in sarcoidosis British Journal of. Hydroxychloroquine and l lysine Jul 15, 2004 OPHTHALMOLOGIC SARCOIDOSIS. Acute anterior uveitis usually clears spontaneously or after treatment with topical corticosteroids.1, 2 Systemic corticosteroids are indicated for treatment of optic. Sarcoidosis - American Family Physician. Sarcoidosis - Diagnosis and treatment - Mayo Clinic. Sarcoidosis Mystery Unraveled - Review of Optometry. Apr 05, 2010 if you go on plaquenil please know that you will require Opthalmological exams to make sure there are no changes to the eye from it. it can cause optic nerve damage. Methtorexate is given for any ocular inflammatory disease such as uveitis. Sarcoidosis can affect almost any organ in the body. But the most common target is the lung. Although doctors do not know the exact cause of sarcoidosis, there is strong evidence that the illness involves an abnormal immune reaction. For example, it is known that the granulomas contain cells from the immune system. Anterior uveitis is by far the most common subtype of uveitis in whites over 80% of cases, but posterior uveitis and panuveitis are more prevalent among blacks.21, 23, 24, 25 Sarcoid uveitis is characteristically bilateral,21, 24, 26 and features of granulomatous uveitis are usually, although not universally, seen on slit-lamp examination.25.