Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine for systemic lupus erythematosus Hydroxychloroquine for hair loss Efectos secundarios de hydroxychloroquine 200 mg Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. For this reason, you can think of antimalarials as a sort of “lupus life insurance.” Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. Any experienced lupus doctor would never describe plaquenil as an immunosuppressant. It does not have the same immunosuppressant effect as the other immunosuppressants we usually talk about imuran, methotrexate, cellcept. and is NEVER used for immunosuppressive therapy, for example in the event of organ transplants. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Is plaquenil an immunosuppressant Hydroxychloroquine Side Effects, Dosage, Uses, and More, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Cost of generic plaquenilHydroxychloroquine cause weight loss Physicians and patients consider hydroxychloroquine an immunosuppressant medication for lack of a more accurate descriptor. Perhaps an immunomodulatory medication would be a better term. The mechanism of action of HCQ has not been fully elucidated and is still a matter of debate, but it clearly has been shown to have anti-inflammatory properties mediated through modulation of the immune system. Reasonably Well Plaquenil FAQ. Is plaquenil an immunosuppresant? Lupus Forums at The.. PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION. Lupus nephritis is successfully treated with immunosuppressive drugs and glucocorticoids. The benefits of these lupus treatments are well known with well-documented improved renal survival and function as well as reduced mortality with treatment 2 – 4. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. PLAQUENIL is not recommended for the treatment of malaria acquired in geographic areas where chloroquine resistance occurs or when the Plasmodium species has not been identified. PLAQUENIL is not recommended for malaria prophylaxis in geographic areas where chloroquine resistance occurs.