Metformin treatment

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  1. streetdream Well-Known Member

    Metformin treatment


    Metformin is the most popular pharmacotherapy to manage Type 2 diabetes. This medication is also widely used as a treatment for weight loss as well as polycystic ovary syndrome in women. Metformin helps with lowering blood sugar and weight loss without causing serious side effects. Metformin is available in tablet form dispensed in dosages of 500, 850, or 1000 mg. The active ingredient in this medication is indeed metformin. Metformin or metformin hydrochloride is considered as part of the biguanide class of drugs, which help with eliminating hyperglycemia (i.e., increased blood glucose levels). Metformin is primarily taken to treat Type 2 diabetes. Metformin is an insulin-sensitizing drug primarily used to treat diabetes, but it can also be used for fertility. Women with PCOS may benefit from taking metformin alone, along with Clomid, or even during IVF treatment. Exactly how metformin improves fertility is unclear. While metformin may be used for the treatment of infertility, it is not a fertility drug. In fact, using it to treat infertility is considered an off-label use. (In other words, pregnancy achievement is not the original intended purpose of this drug.) What is this medication? To understand what metformin does, you first need to know what insulin resistance is. Insulin resistance is when the body's cells stop reacting to normal levels of insulin. As a result, the body thinks that there is not enough insulin in the system. This triggers the production of more insulin than your body needs.

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    Metformin overdose symptoms and treatment Although not common, a metformin overdose can result in serious side effects that could be fatal. In case of a drug overdose, you should stop taking this medication and seek medical attention immediately. Diabetes Care. 2018 Mar;413547-553. doi 10.2337/dc17-2231. Epub 2018 Jan 5. Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney. Metformin use for more than 2 years has a significant reduction in neurodegenerative disease; it is neuroprotective as well as promoting neurogenesis. Though the mechanism between metformin and neurodegenerative disease is uncertain, it is known to cross the blood brain barrier and has pleiotropic effects.

    The UK Prospective Diabetes Study, a large clinical trial performed in 1980-90s, provided evidence that metformin reduced the rate of adverse cardiovascular outcomes in overweight patients with type 2 diabetes relative to other antihyperglycemic agents. Treatment guidelines for major professional associations including the European Association for the Study of Diabetes, the European Society for Cardiology and the American Diabetes Association, now describe evidence for the cardiovascular benefits of metformin as equivocal. In 2017, the American College of Physicians's guidelines were updated to recognize metformin as the first-line treatment for type-2 diabetes. For example, a 2014 review found tentative evidence that people treated with sulfonylureas had a higher risk of severe low blood sugar events (RR 5.64), though their risk of non-fatal cardiovascular events was lower than the risk of those treated with metformin (RR 0.67). There was not enough data available at that time to determine the relative risk of death or of death from heart disease. study known as the Diabetes Prevention Program, participants were divided into groups and given either placebo, metformin, or lifestyle intervention and followed for an average of three years. Metformin treatment of people at a prediabetes stage of risk for type 2 diabetes may decrease their chances of developing the disease, although intensive physical exercise and dieting work significantly better for this purpose. The intensive program of lifestyle modifications included a 16-lesson training on dieting and exercise followed by monthly individualized sessions with the goals of decreasing weight by 7% and engaging in physical activity for at least 150 minutes per week. The incidence of diabetes was 58% lower in the lifestyle group and 31% lower in individuals given metformin. Among younger people with a higher body mass index, lifestyle modification was no more effective than metformin, and for older individuals with a lower body mass index, metformin was no better than placebo in preventing diabetes. Metformin may rarely cause a serious, life-threatening condition called lactic acidosis. Your doctor will probably tell you not to take metformin. Also, tell your doctor if you are over 65 years old and if you have ever had a heart attack; stroke; diabetic ketoacidosis (blood sugar that is high enough to cause severe symptoms and requires emergency medical treatment); a coma; or heart or liver disease. Taking certain other medications with metformin may increase the risk of lactic acidosis. Tell your doctor if you are taking acetazolamide (Diamox), dichlorphenamide (Keveyis), methazolamide, topiramate (Topamax, in Qsymia), or zonisamide (Zonegran). Tell your doctor if you have recently had any of the following conditions, or if you develop them during treatment: serious infection; severe diarrhea, vomiting, or fever; or if you drink much less fluid than usual for any reason. You may have to stop taking metformin until you recover. If you are having surgery, including dental surgery, or any major medical procedure, tell the doctor that you are taking metformin.

    Metformin treatment

    The management of diarrhea caused by metformin Diabetes Daily Post, Metformin Treatment in Patients With Type 2 Diabetes and Chronic.

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  7. Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes, particularly in people who are.

    • Metformin - Wikipedia.
    • Metformin and Alzheimer's A Potential New Therapy?.
    • Is Metformin The Ideal Treatment for PCOS?.

    Metformin is used to treat people with type 2 diabetes. It is sometimes used in combination with insulin or other medications. Learn about side effects, interactions. Metformin is an oral antidiabetic drug for the treatment of diabetes. Learn how it works to lower blood sugar, its benefits, side effects & use for weight loss. Why So Many People with Diabetes Stop Taking Metformin. “There has never been as many diabetes treatment options available as there are now,” explained Robinson. “But doctors look at.

     
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