It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Chloroquine nursing implications Diseases treated with plaquenil Can hydroxychloroquine cause skin pigmentation Hydroxychloroquine Oral tablet 200mg Drug Medication Dosage information. Learn about the reported side effects, related class drugs, and how these medications will affect your daily lifestyle. Visit for more details. Do not exceed 600 mg or 6.5 mg/kg 5 mg/kg base per day, whichever is lower, as the incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. Corticosteroids and salicylates may be used in conjunction with PLAQUENIL, and they can generally be decreased gradually in dosage or eliminated after a maintenance. Jan 18, 2019 The current recommendation is a daily dose that does not exceed 6.5 mg/kg/day that is milligrams per kilograms per day. There are approximately 2.2 lbs. in a KG. The pills come in 200mg tablets. Most people who are on this drug are on either 200MG once a day or 200 mg twice a day. The safety break point comes at around 135 Lbs. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. 2 pills per day hydroxychloroquin Hydroxychloroquine Reviews Everyday Health, Plaquenil Dosage Guide - Plaquenil canada One PLAQUENIL tablet contains 200 mg of hydroxychloroquine sulfate, which is equivalent to 155 mg base. Take PLAQUENIL with a meal or a glass of milk. Malaria Prophylaxis. Adults. 400 mg 310 mg base once weekly on the same day of each week starting 2 weeks prior to exposure, and continued for 4 weeks after leaving the endemic area. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. What can Hydroxychloroquine Plaquenil do to my eyes?. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. This is a really ambiguous instruction, and I hope it isn't on your pill bottle. Take 2 pills daily can mean either to take 2 pills at the same time once a day or to take 2 pills one each at different times. The pharmacist's instructions should be much clearer, such as "take one pill every 12 hours." Hydroxychloroquine is sometimes given only once per week. Choose the same day each week to take this medicine if you are on a weekly dosing schedule. Take hydroxychloroquine with a meal or a glass of milk. To prevent malaria Start taking the medicine 2 weeks before entering an area where malaria is common. Continue taking the medicine. Hydroxychloroquine is sometimes given only once per week. Choose the same day each week to take this medicine if you are on a weekly dosing schedule. Take hydroxychloroquine with a meal or a glass.