With Lupus and immunosuppressants, I am staying home as much as possible, but there are a few times I'm going to have to go out. Since being diagnosed with Lupus and taking the normal meds, particularly Plaquenil and Prednisone (over about 6 years), I gained about 45 pounds. Doctor took me off of plaquenil Does plaquenil help with allergies Plaquenil rash To check all the drugs that have ingredients of hydroxychloroquine sulfate and Weight increased Weight increased and drugs with ingredients of hydroxychloroquine sulfate 1,519 reports How severe was Weight increased and when was it recovered Weight increased in Plaquenil Now after dropping the second 200mg again an increase in pain which I am managing and tiredness and even greater weight loss. I had at the start of treatment put on weight but had put it down to inactivity but now believe Hydroxychloroquine had actually made me gain weight. Unfortunately, a LOT of the meds we're prescribed come with weight gain as a side effect just ONCE I wish the side effects would be "become irresistible" but I've yet to hear about that drug trial Usually it's an issue of one or two things sometimes both. Some of these drugs increase your appetite and cravings. Well, now I've been exercising at almost my pre-Lupus rate (ran a marathon a year before), eating a more moderate diet (clean protein, vegs & fruits), and am no longer taking that weight & bloat causing Prednisone (off Pred almost 2 yrs now). My question: Do you feel like you've gained weight on Plaquenil (ie without Prednisone)? Part of that is due to less exercise, part due to having no appetite thus feeling like anything I can get down is ok. Do hydroxychloroquine cause weight gain Plaquenil and loss of appetite - Lupus - MedHelp, Hydroxychloroquine Reviews Everyday Health If i go off plaquenil can i go back on Apr 03, 2008 Hi everyone. I know this seems shallow and there are more important things in life like getting healthy but I have a question for those who are taking or have taken Medrol and or Plaquenil. Has anyone experienced weight gain? I have been reading up on side effects and weight gain and swollen face. Medrol, Plaquenil and weight gain - Sclero Forums MAIN.. Weight gain while on Plaquenil? lupus. Does Plaquenil Cause Weight Gain - Ironstone Vineyards. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. I appear to have gradually lost weight and down to a size 8 in clothes but was a size 12. Is this due to the medication or not, I dont enjoy my food as I did but eat ok. Why is it that I take this medication and yet why do I keep getting this bursitis in my hips. I cant walk very far without suffering. Oct 12, 2016 Which Drugs Cause Weight Gain, Loss in RA? by U. S. Medicine Oct 12, 2016 PHILADEPHIA—Unintentional weight loss often can help predict long-term outcomes in patients with rheumatoid arthritis RA.