She said the muscles were a touch irritated as well. Diagnosed small fiber p neuropathy due to autoimmune issues and recommended I get a second opinion from a different rheumatologist and for treatment of the neuropathy. Hydroxychloroquine sulfate prices Treatment of chloroquine resistant malaria in pregnancy Plaquenil dry mouth If your main symptoms are neuropathy related, then stick with something that is KNOWN to help immune mediated SFN, like IVIG. Plaquenil is primarily used to help with some of the symptoms of Sjogren's.reduce fatigue, and joint pain. It is also thought it help slow progression but not well documented for this. There is a possibility that Plaquenil may affect nerve conduction. Given your history I would make an appointment to see your doctor. You might want to click on the Drugs A to Z tab at the top of this page. You can find out lots of information on peripheral neuropathy. Small Fiber Neuropathy SFN, a type of peripheral neuropathy PN, is a fairly common chronic condition that can develop at any age, with the disease most prevalent in the elderly. While its prevalence is unknown, 1 an estimated 15 million to 20 million people in the U. S. over age 40 have some type of PN. 2 To date, there is no cure for SFN. I know this is true as it reversed itself last time, though it was not this bad. Thanks for the information, Tammy15 mg prednisone150 mg Imuran.5 mg clonazepam Hi Tammy, This is what Wikipedia says about treatment of Small Fiber Neuropathy: Treatment is based on the underlying cause, if any. Usually she said small fiber neuropathy is reversible, with good aggressive treatment. Can plaquenil help with small fiber neuropathy Small-Diameter Nerve Fiber Neuropathy in Systemic Lupus., Can plaquinel cause neuropathy? - Saposin b binds chloroquineCan i take a multivitamin with plaquenil However, neuropathies affecting smaller-fiber nerves that lack this myelin coating cannot be detected with these tests. 6. Special diagnostic tests, including the technique of superficial, punch skin biopsies small biopsies of three millimeters and not requiring any stitches, can help in the diagnosis. Peripheral Neuropathy and Sjogren's. IVIG for Small Fiber Neuropathy. A Guide Living With Small Fiber Neuropathy Is This Condition.. And small-fiber neuropathy. Heterozygous mutations in TRPA1, which encodes the transient receptor potential cation channel, can cause familial episodic pain syndromes, and variants of genes coding for the voltage-gated sodium channels Nav1.8 SCN10A and Nav1.9 SCN11A lead to small-fiber neuropathy and congenital insensitivity to pain, The pannus hardens and can impinge and compress nerves. There is good news, though. In general, neuropathy caused by rheumatoid disease is mild. If you’re experiencing what feels like neuropathic pain in your feet or hands, talk to your rheumatologist. There are effective drugs available that can relieve the pain. But not so fast, these tests only detect large nerve fiber neuropathy, which usually develops years after suffering with small fiber sensory neuropathy. Well you can stop worrying because there are tests available that can diagnose this condition.