But if you get a rash or more serious reaction when you take one of these drugs, you may have a sulfa allergy. Sulfa drugs, also called sulfonamides, include antibiotics and other types of drugs. Around 3% of people have some type of reaction to them. Chloroquine lysing the endosome Hydroxychloroquine cystic fibrosis Have had an allergic reaction to a related product ask your doctor or pharmacist. The symptoms of an allergic reaction may include an asthma attack, facial swelling, skin rash or hay fever. Ask your doctor about the risks and benefits of taking Plaquenil while you are pregnant. When Plaquenil is taken for long periods of time, there is an increased Discontinuation of hydroxychloroquine could decrease codeine plasma concentrations and increase morphine plasma concentrations resulting in prolonged opioid adverse reactions, including hypotension, respiratory depression, profound sedation, coma, and death. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, She’ll decide whether to take you off the drug and how to treat your symptoms. Tell your doctor right away if you think you’re having a reaction to a sulfa drug. Delayed allergic reaction to plaquenil Prednisone Oral Route Side Effects - Mayo Clinic, Plaquenil hydroxychloroquine sulfate dose, indications. Retinal toxicity dosage hydroxychloroquineChloroquine resistance map malaria Friday morning, the rash had transmogrified into full blown hives up the back of my right leg. Lucky me! An allergic reaction! I hauled myself to a step-in clinic at the local hospital where the nurse practitioner explained that since I took the drug for six weeks it would take six weeks for it to get out. Chronic Illness My Bad Experience with Plaquenil Mrs. Ram's Jams. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Cutaneous reactions to antimalarial agents were commonly observed in the treatment of psoriasis and psoriatic arthritis. Similar reactions are unusual in patients with lupus erythematosus LE. We have observed disease-specific cutaneous reactions to hydroxychloroquine in the treatment of DM. Aug 14, 2017 Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The reaction can also cause these serious skin reactions Sulfonamide drug hypersensitivity syndrome Rash, fever, and organ problems begin within 1 to 2 weeks after you start the drug. Drug eruption Red or swollen, rounded patches form in 30 minutes to 8 hours. Stevens Johnson syndrome This potentially.