Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Effect of chloroquine on sle How to treat nausea from plaquenil Jan 05, 2020 In early cases of toxicity, visual fields will typically reveal a paracentral scotoma. If a 24-2 or 30-2 field is performed, be way of overlooking the 2-degree field of sparing seen on 10-2 fields; in these tests, a small central defect may be seen instead. Hydroxychloroquine may not prevent malaria in all cases. If you experience fever or other symptoms of illness, seek immediate medical attention. retinal or visual field problems from other. Nov 18, 2011 To analyze Humphrey visual field HVF findings in hydroxychloroquine HCQ retinal tests were interpreted retrospectively in this observational case series of 15 patients with HCQ toxicity. Patients seen at Lahey Clinic were identified by. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Plaquenil visual field Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Hydroxychloroquine liverMethotrexate and plaquenil for lupus Visual field defect is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 10+ years, also take medication Methotrexate, and have Osteoporosis. Will you have Visual field defect with Plaquenil - eHealthMe. Humphrey visual field findings in hydroxychloroquine toxicity. Early Paracentral Visual Field Loss in Patients Taking.. Visual fields are examined by the use of static or kinetic perimetry. The procedure is performed separately for each eye, and measures the combined function of the retina, the optic nerve, and the intracranial visual pathway. It is used clinically to detect or monitor field loss due to disease at any of these locations. Dec 04, 2014 Visual fields. The subjective component to HCQ retinopathy screening is an automated visual field testing the central 10° of vision. The earliest signs of HCQ retinopathy on a central visual field may present as a cluster of paracentral points with decreased sensitivity. These points may be only mildly depressed. Apr 10, 2019 Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes.