Type in a drug name to check for interactions with hydroxychloroquine. View interaction reports for hydroxychloroquine and the medicines listed below. The relevance of a particular drug interaction to a specific individual is difficult to determine. How long does it take for plaquenil to kick in Imodium plaquenil Plaquenil reviews I was diagnosed with RA in march and have been on increasing dose of methotrexate. Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Thanks Summary Drug interactions are reported among people who take Methotrexate and Plaquenil together. This study is created by eHealthMe based on reports of 23,242 people who take Methotrexate and Plaquenil from Food and Drug Administration FDA, and is updated regularly. We would like to show you a description here but the site won’t allow us. In some cases, they may not be available in every strength or form as the brand-name drug. Always consult your healthcare provider before starting or stopping any medication. Hydroxychloroquine and methotrexate interaction Plaquenil Oral Interactions with Other Medication, Methotrexate and Plaquenil drug interactions - eHealthMe Can plaquenil cause extreme fatiguePlaquenil retinal toxicity octPlaquenil eye exam costPlaquenil screening guidelines Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine - Side Effects, Dosage, Interactions.. . Interactions among Low Dose of Methotrexate and Drugs Used in.. Description and Brand Names. Drug information provided by IBM Micromedex US Brand Name. Plaquenil; Descriptions. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. Methotrexate–hydroxychloroquine combination therapy may cause lower disease activity in early RA than methotrexate monotherapy. Methotrexate monotherapy as first early RA treatment seems to lead to more treatment intensification. I started on Hydroxychloroquine and prednisone at the end of December. Just saw rheumy yesterday because the prednisone wasn't having any affect on 20 mg/day and my rheumy didn't want to increase the prednisone any higher. So she has put me on methotrexate. She said I can take the dose all at.