B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions. Buy chloroquine phosphate fish 20 gallon Plaquenil and thyroid Obgyn plaquenil lupus Protect the nails when performing wet work like washing dishes by using rubber gloves and cotton glove liners. Avoid excess contact with water or chemicals including nail polish remover which can cause dryness. Use moisturizer on your nails multiple times per day and reapply the moisturizer after your hands come in contact with water. Aug 18, 2011 Answer. Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong. Apr 10, 2019 Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Call your doctor at once if you have B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100). Plaquenil and nail changes Will you have Nail abnormalities with Plaquenil - eHealthMe, Skin Discoloration and Plaquenil - Arthritis Information Chloroquine tablets lloyds Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine and skin darkening Hi All. - LUPUS UK. I would love to hear from anyone who's gone on meds Plaquenil or something else to prevent their Sjogren's from getting worse--or has decided against it. I was diagnosed last year. I'm in my 50s and an anti-inflammatory diet has helped me a lot. 100% free of added sugars and gluten since diagnosis. A recent large study of people with cardiovascular disease found that hydroxychloroquine Plaquenil does not increase the risk of infection and methotrexate increases the risk of infection only slightly. The concern with immune suppression is that the virus could replicate more freely and cause more severe or extensive disease, says Dr. Winthrop. What is drug-induced nail disease? Drug-induced nail disease is diagnosed when a medication affects nail growth or structure. Drugs may cause Changes to the shape of the nail nail deformity Changes in the texture or composition of the nail nail dystrophy Abnormality of the tissues around the nail paronychia Pigmentation of the nail plate.