Treatment of chloroquine resistant malaria in pregnancy

Discussion in 'Chloroquine Without A Doctors Prescription' started by JulyCat, 25-Feb-2020.

  1. Voron15 Well-Known Member

    Treatment of chloroquine resistant malaria in pregnancy

    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Intermittent preventive treatment of malaria in pregnancy IPTp with sulphadoxine-pyrimethamine SP reduces the incidence of low birth-weight, pre-term delivery, intrauterine growth-retardation and maternal anaemia. However, the public health benefits of IPTp are declining due to SP resistance. The combination of azithromycin and chloroquine. Vivax malaria. Chloroquine remains an effective treatment for vivax malaria in most of the world, although resistance that emerged in Papua New Guinea and Indonesia is spreading. ACTs apart from artesunate-SP are also highly effective for treatment of vivax malaria, and parenteral artesunate is highly effective in the severe vivax disease 31. Nov 25, 2019 There are no controlled data in human pregnancies. Congenital anomalies were reported in the offspring of one woman being treated with chloroquine 250 to 500 mg daily during pregnancy for SLE; however, chloroquine has been used in the prophylaxis and treatment of malaria during pregnancy without evidence of fetal harm.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Treatment of chloroquine resistant malaria in pregnancy

    Treatment of chloroquine-resistant malaria during pregnancy., Management of malaria in pregnancy - PubMed

  2. Plaquenil in ana pregnancy
  3. Infections should receive chloroquine prophylaxis 300 mg base po once a week during pregnancy.

    • Guidelines for Treatment of Malaria in the United States..
    • Chloroquine Use During Pregnancy.
    • Prophylactic use of antimalarials during pregnancy.

    Usage of Chloroquine during pregnancy should be avoided except in the prophylaxis or treatment of malaria when the benefit outweighs the potential risk to the fetus. Radioactively tagged Chloroquine administered intravenously to pregnant pigmented CBA mice passed rapidly across the placenta and accumulated selectively in the melanin structures of the fetal eyes. For pregnant women, chloroquine is the preferred treatment for malaria. Quinine, proguanil and clindamycin typically are used for pregnant people with malaria that is resistant to chloroquine. When To Call a Professional Chloroquine is the drug of choice for the treatment of non-falciparum malaria but chloroquine-resistant P. vivax has been reported in the Indonesian archipelago, the Malay Peninsula, including Myanmar, and eastward to Southern Vietnam.

  4. makiavelli Well-Known Member

    We present the case of two twin brothers with surfactant protein C deficiency who were treated with hydroxychloroquine for three years, with apparent success. Hydroxychloroquine and Surfactant Protein C Deficiency. Hydroxychloroquine and Surfactant Protein C Deficiency Request PDF Surfactant Deficiency Causes & Reasons - Symptoma®
  5. CADET Well-Known Member

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  6. cjart New Member

    Chloroquine inhibits autophagic flux by decreasing. Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion. Mauthe M12, Orhon I1, Rocchi C13, Zhou X14, Luhr M5, Hijlkema KJ1, Coppes RP13, Engedal N5, Mari M12, Reggiori F12.

    Assessment of chloroquine treatment for modulating.