Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. This medication is used to kill the malaria parasites living inside red blood cells. Will hydroxychloroquine cause high blood pressure Chloroquine inhibits autophagy in mice Infections should receive chloroquine prophylaxis 300 mg base po once a week during pregnancy. After delivery, patients with normal G6PD activity should be treated with primaquine or tafenoquine or continue with chloroquine prophylaxis for a total of 1 year. Oct 30, 2015 In most affected areas around the world, a combination treatment of chloroquine CQ and primaquine PQ was introduced in the 1950s to treat P. vivax blood and liver infections 5, 6. Primaquine is used after other medications such as chloroquine have killed the malaria parasites living inside red blood cells. Primaquine then kills the malaria parasites living in other body tissues. This prevents the return of the infection. Both drugs are needed for a complete cure. Both drugs may be needed for a complete cure and to prevent the return of infection (relapse). In some cases, you may need to take a different medication (such as primaquine) to kill the malaria parasites living in other body tissues. Chloroquine and primaquine treatment Treatment of Malaria – Malaria Site, Effectiveness of combined chloroquine and primaquine. Plaquenil maculopathy reportPlaquenil oct changesPlaquenil and ironChloroquine and proguanil doseOcular testing for plaquenil Primaquine is active as a chloroquine-resistance reverser at concentrations that could be clinically relevant. As primaquine and chloroquine are already used together in the treatment of P. vivax, this is potentially a cheap way of reviving and extending the life of chloroquine. Chloroquine and primaquine combining old drugs as a new.. Primaquine Oral Uses, Side Effects, Interactions, Pictures.. Latest research finds primaquine improves haemoglobin by day.. INDICATIONS. Primaquine phosphate is indicated for the radical cure prevention of relapse of vivax malaria. DOSAGE AND ADMINISTRATION. Primaquine phosphate is recommended only for the radical cure of vivax malaria, the prevention of relapse in vivax malaria, or following the termination of chloroquine phosphate suppressive therapy in an area where vivax malaria is endemic. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with primaquine. This list is not complete. Other drugs may interact with primaquine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Primaquine is an antimalarial agent and is the essential co-drug with chloroquine in treating all cases of malaria. In the blood, malaria parasites break down a part of the red blood cells known as haemoglobin.