In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Chloroquine ciprofloxacin Deae dextran chloroquine method Hydroxychloroquine is a well tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity. Within the eye, hydroxychloroquine negatively impacts the cornea, ciliary body, and retina. Visual problems. There is a small risk that hydroxychloroquine can damage your retina part of the eye, and this increases with long-term use and higher dosage. Your doctor will advise you on a safe dose to take according to your weight, and you will need to have regular monitoring of your eyes. Your doctor may want your eyes be checked by an ophthalmologist eye doctor. This medicine may cause muscle and nerve problems. Check with your doctor right away if you have muscle weakness, pain, or tenderness while using this medicine. Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Eye problems on hydroxychloroquine Hydroxychloroquine MedlinePlus Drug Information, Hydroxychloroquine Side-effects, uses, time to work Can plaquenil cause weight loss In rare cases, hydroxychloroquine can cause visual changes or loss of vision. Such vision problems are more likely to occur in individuals taking high doses for many years, individuals 60 years or older, or those with significant kidney disease. At the recommended dose, development of visual problems due to the medication is rare. Hydroxychloroquine Plaquenil. Hydroxychloroquine Oral Route Precautions - Mayo Clinic. Hydroxychloroquine and macular degeneration - NRAS. Macular Society Eye screening for patients taking hydroxychloroquine Hydroxychloroquine is a medication used to treat several conditions including rheumatoid arthritis, systemic lupus erythematosus, some skin conditions especially photosensitive ones and others that involve inflammation. It was previously used in the treatment and Hydroxychloroquine-related eye problems were once considered rare, but better detection methods now show that they occur in about 7 percent of patients. The risk increases with a higher dose and longer therapy. Vision risks. Hydroxychloroquine is dosed according to body weight. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. If you do, your risk of eye problems will.