Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Macular degeneration caused by plaquenil Hydroxychloroquine sulphate tablets zy-q 300 Plaquenil cause dizziness after 2 years Hydroxychloroquine abuse Nov 14, 2006 Someone else told me that plaquenil could take up to a year to work. Others have told me that it only took a few months for them to feel the effects. Everyone is different. I can tell you that plaquenil is the safest of all of the DMARDs. If you're going to stay on a DMARD for a long time, plaquenil is the one to be on. Best of luck on the. Hello kelpie21, It can be a hard road, can't it? Hydroxychloroquine does take a while to take effect. Arthritis UK gives a figure of around 12 weeks, whilst the American College of Rheumatology says, "symptoms can start to improve after 1-2 months, but it may take up to 6 months before the full benefits are felt". I had a skin rash from plaquenil hydroxychloroquine. I was put on a 21 day taper of prednisone. How long befor more I had a skin rash from plaquenil hydroxychloroquine. I was put on a 21 day taper of prednisone. How long before the prednisone increases my odds of catching viruses? Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. How long before plaquenil works Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, How long until Hydroxychloroquine takes effect - LUPUS UK Plaquenil canadaChloroquine in chikungunya I am having severe RA again in my feet and ankles. Happens about at the end of every month now. Even since I've started the meds. I am on Plaquenil right now, but I am wondering how well it works since my pain has come back. I have heard some people switch over to Methotrxate if the Plaquenil doesn't work. 4 replies Arthritis Board Index plaquenil how long to work. How long does it take for plaquenil hydroxychloroquine to.. Hydroxychloroquine Plaquenil. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Most people who take Plaquenil also take other medicines for pain and stiffness. How does Plaquenil work? Plaquenil changes the way your immune system works. Apr 10, 2019 To prevent malaria Start taking Plaquenil 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay and for at least 8 weeks after you leave the area. Hi Guys, I haven't been here for a while - just checked in and found this question on Plaquenil - for me it took approx nine weeks to begin to work - I'm only taking 200mg per day so far - it seemed to stop working a few weeks later - most days are pretty good I s'pose but I drop nearly every afternoon.