Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. What is plaquenil medication used for Plaquenil muscle toxicity Chronic Cutaneous Lupus. –Discoid Lupus. •Discoid lesions on face, scalp & ears •Can occur on mouth and lips •Disfiguring scarring & hair loss •Goes deep into skin to affect hair follicles •Discoloration-white centers and dark edges •Can develop skin cancer within lesions •5 -10% can develop systemic lupus. In general patients with lichen planopilaris may have itching of the scalp and some may have increased hair shedding. They may also have burning, pain and tenderness in the scalp. Some patients note that the scalp is tender when the hairs are moved. There may be redness in the scalp and some scale. Doxycyline and tetracycline have been tried because of their anti-inflammatory effects. Plaquenil has been used because of its benefit in patients with discoid lupus erythematosus, another lymphocyte-mediated scarring alopecia. Isotretinoin, dapsone, and thalidomide have all been tried. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. How can plaquenil scarring alopecia Central centrifugal cicatricial alopecia DermNet NZ, Lichen Planopilaris — Canadian Hair Loss Foundation Plaquenil and vision If that isn't an option, go to a doctor. If it isn't that deeply grown in, removal is fairly simple. If it is and that's what they're designed to do -- grow into your tissue, the piercer or MD will use a scalpel to remove it. The scarring should be minimal. I have scarring alopecia should I go on plaquenil - Answers. Lichen Planopilaris Treatment Dermatology Education. Will you have Hair loss with Plaquenil - eHealthMe. You are supposed to have a blood test every month to check on your liver and kidneys as long term use can affect them. I was told also to keep an eye out for 'floaters' in my eyes, as Plaquenil can cause macular damage to your retinas. I'm only on a low dose, but now have a black line floating over my eye. This drug is also referred to under its popular trade name “Plaquenil” Hydroxychloroquine is a type of anti-inflammatory medication used to treat some types of hair loss such as lichen planopilaris and sometimes discoid lupus and frontal fibrosing alopecia. Jun 15, 2017 Treatment depends on how much of the scalp is affected and how quickly the condition progresses. A high or moderate potency steroid cream is often effective in treating lichen planopilaris. If this is not effective, steroid injections into skin lesions, or systemic corticosteroids taken by mouth may be considered.