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    Privacy Statement At Wilson-Hite Insurance, Inc., we are committed to protecting your privacy as a visitor to this Web site and as our customer. To our visitors and to our customers, we offer this pledge: Wilson-Hite Insurance is the owner of the information, which is collected on this Web site. PACKAGE LEAFLET: INFORMATION FOR THE USER What Phenergan Tablets are used for Phenergan Tablets are used to treat the following conditions: • For short term use: to treat adults with difficulty sleeping (insomnia) • To treat allergic conditions such as hay fever or rashes (like nettle rash or hives) • To treat or stop you feeling sick (nausea) or being sick (vomiting) such as travel sickness • For short term use: as a sedative for children aged 5 years and above Phenergan 25 mg Tablets promethazine hydrochloride Is this leaflet hard to see or read? What you need to know before you take Phenergan Tablets Phone 08 for help Read all of this leaflet carefully before you start taking this medicine because it contains important information for you. • Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you. You may need to read it again • Ask your pharmacist if you need more information or advice • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. • You must talk to a doctor if you do not feel better or if you feel worse after 7 days. Do not take this medicine if:  The person taking the medicine is under 5 years of age  You are allergic (hypersensitive) to promethazine hydrochloride or any of the other ingredients of Phenergan Tablets (listed in Section 6 below). The signs of an allergic reaction include: a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue  You are taking a medicine for depression called a monoamine oxidase inhibitor (MAOI). Also do not take Phenergan Tablets if you have stopped taking one of these MAOI medicines within the last 14 days. If you are not sure ask your doctor or pharmacist (see “Taking other medicines” section below)  The person is unconscious (in a coma) or suffers from severe dizziness, drowsiness or headache Do not take this medicine if any of the above applies to you. Contents of the pack and other Information Warnings and precautions Check with your doctor or pharmacist before taking your medicine if  You have difficulty breathing, wheezing, tightness in the chest (asthma) or an infection in your lungs (bronchitis)  You have epilepsy  You have any serious heart problems  You have liver or kidney problems  You have a stomach blockage or difficulty passing water 1.

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    PACKAGE LEAFLET: INFORMATION FOR THE USER PHENERGAN® 25mg TABLETS / PROMETHAZINE HYDROCHLORIDE 25mg TABLETS (promethazine hydrochloride) This medicine is available as any of the above names but will be referred to as Phenergan Tablets throughout the following leaflet. Read all of this leaflet carefully before you start taking this medicine because it contains important information for you. • Ask your pharmacist if you need more information or advice. WHAT PHENERGAN TABLETS ARE AND WHAT THEY ARE USED FOR Phenergan Tablets contain a medicine called promethazine hydrochloride. • Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you. • If you get any side effects, talk to your doctor or pharmacist. This belongs to a group of medicines called phenothiazines. This includes any possible side effects not listed in this leaflet. • You must talk to a doctor if you do not feel better or if you feel worse after 7 days. What Phenergan Tablets are and what they are used for 2. It works by blocking a natural substance (histamine) that your body makes during an allergic reaction. What you need to know before you take Phenergan Tablets 3. It also works directly on the brain to help you feel more relaxed. What Phenergan Tablets are used for Phenergan Tablets are used to treat the following conditions: • For short term use: to treat adults with difficulty sleeping (insomnia) • To treat allergic conditions such as hay fever or rashes (like nettle rash or hives) • To treat or stop you feeling sick (nausea) or being sick (vomiting) such as travel sickness • For short term use: as a sedative for children aged 5 years and above 2. WHAT YOU NEED TO KNOW BEFORE YOU TAKE PHENERGAN TABLETS Do not take this medicine if: • The person taking the medicine is under 5 years of age • You are allergic (hypersensitive) to promethazine hydrochloride or any of the other ingredients of Phenergan Tablets (listed in Section 6 below). The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged. Below is a text only representation of the Patient Information Leaflet. The original can be viewed in PDF format using the link above. The text only version may be available from RNIB in large print, Braille or audio CD. What Phenergan Tablets are and what they are used for Phenergan Tablets contain a medicine called promethazine hydrochloride. For further information call RNIB Medicine Leaflet Line on 08. This belongs to a group of medicines called phenothiazines.

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    Day 1: 10 mg PO before breakfast, 5 mg after lunch and after dinner, and 10 mg at bedtime Day 2: 5 mg PO before breakfast, after lunch, and after dinner and 10 mg at bedtime Day 3: 5 mg PO before breakfast, after lunch, after dinner, and at bedtime Day 4: 5 mg PO before breakfast, after lunch, and at bedtime Day 5: 5 mg PO before breakfast and at bedtime Day 6: 5 mg PO before breakfast Immediate-release: ≤10 mg/day PO added to disease-modifying antirheumatic drugs (DMARDs) Delayed-release: 5 mg/day PO initially; maintenance: lowest dosage that maintains clinical response; may be taken at bedtime to decrease morning stiffness with rheumatoid arthritis Take with meal or snack High-dose glucocorticoids may cause insomnia; immediate-release formulation is typically administered in morning to coincide with circadian rhythm Delayed-release formulation takes about 4 hours to release active substances; thus, with this formulation, timing of dose should take into account delayed-release pharmacokinetics and disease or condition being treated (eg, may be taken at bedtime to decrease morning stiffness with rheumatoid arthritis) Allergic: Anaphylaxis, angioedema Cardiovascular: Bradycardia, cardiac arrest, cardiac arrhythmias, cardiac enlargement, circulatory collapse, congestive heart failure, fat embolism, hypertension, hypertrophic cardiomyopathy in premature infants, myocardial rupture after recent myocardial infarction, pulmonary edema, syncope, tachycardia, thromboembolism, thrombophlebitis, vasculitis Dermatologic: Acne, allergic dermatitis, cutaneous and subcutaneous atrophy, dry scalp, edema, facial erythema, hyper- or hypopigmentation, impaired wound healing, increased sweating, petechiae and ecchymoses, rash, sterile abscess, striae, suppressed reactions to skin tests, thin fragile skin, thinning scalp hair, urticaria Endocrine: Abnormal fat deposits, decreased carbohydrate tolerance, development of cushingoid state, hirsutism, manifestations of latent diabetes mellitus and increased requirements for insulin or oral hypoglycemic agents in diabetics, menstrual irregularities, moon facies, secondary adrenocortical and pituitary unresponsiveness (particularly in times of stress, as in trauma, surgery, or illness), suppression of growth in children Fluid and electrolyte disturbances: Fluid retention, potassium loss, hypertension, hypokalemic alkalosis, sodium retention Gastrointestinal: Abdominal distention, elevation of serum liver enzymes levels (usually reversible upon discontinuance), hepatomegaly, hiccups, malaise, nausea, pancreatitis, peptic ulcer with possible perforation and hemorrhage, ulcerative esophagitis General: Increased appetite and weight gain Metabolic: Negative nitrogen balance due to protein catabolism Musculoskeletal: Osteonecrosis of femoral and humeral heads, Charcot-like arthropathy, loss of muscle mass, muscle weakness, osteoporosis, pathologic fracture of long bones, steroid myopathy, tendon rupture, vertebral compression fractures Neurologic: Arachnoiditis, convulsions, depression, emotional instability, euphoria, headache, increased intracranial pressure with papilledema (pseudotumor cerebri; 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