Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine metabolism Chloroquine vs chloroquinine Plaquenil pill side effect For treatment of lupus Adults—200 to 400 milligrams mg taken as a single dose or in two divided doses once a day. However, dose is usually not more than 400 mg once a day. Children—Use and dose must be determined by your doctor. Missed Dose. If you miss a dose of this medicine, take it as soon as possible. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects. INTRODUCTION Hydroxychloroquine HCQ is an alkalinizing lysosomatropic drug that accumulates in lysosomes where it inhibits some important functions by increasing the pH. HCQ has proved to be effective in a number of autoimmune diseases including systemic lupus erythematosus SLE. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine lupus dose Hydroxychloroquine Uses, Dosage & Side Effects -, Treating Lupus with Anti-Malarial Drugs Johns Hopkins. Chloroquine phosphate for malariaHydroxychloroquine keratopathyPlaquenil bronchospasmZydus hydroxychloroquine side effectsHow long for plaquenil rash to go away Hi Tilcara. Here is some information about this unfortunate side effect from 'The Lupus Encyclopedia'; "One of the potential long-term side effects of using anti-malarial medications such as hydroxychloroquine, chloroquine, and quinacrine is the development of dark-coloured patches on the skin. Hydroxychloroquine dosage Hi All, A general. - LUPUS UK. Hydroxychloroquine in systemic lupus erythematosus SLE.. Plaquenil Hydroxychloroquine for Lupus - LupusCorner. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. For individuals with significant risk factors daily dose of hydroxychloroquine sulfate 5.0 mg/kg base of actual body weight, subnormal glomerular filtration, use of tamoxifen citrate or concurrent macular disease monitoring should include annual examinations which include BCVA, VF and SD-OCT; for individuals without significant risk factors. People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to go up when a person takes the medication over 5 years or has a cumulative dose of more than 1000 grams.