Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. How much is to much plaquenil Hydroxychloroquine plaquenil for malaria protection Plaquenil and eye exams I have a question to ask anyone on plaquenil. After taking it, does it make you feel all of sudden really tired? I recently started taking it in September and it seems like after about 5-10 minutes of taking it, I feel super tired and sleepy. I have read about the side effects and I do get the stomache discomfort but is the tiredness normal? Note that chloroquine is not used frequently in the United States and has been replaced by the use of hydroxychloroquine because the latter has fewer side effects. The Plaquenil Problem “Plaquenil toxicity is very distinctive,” said Michael F. Marmor, MD, professor of ophthalmology at Stanford University. Hi I have taken Plaquenil since 1995 i was diagnosed with Lupus sle i have never had that side effect. though i do know that if you take too much fiber you will get constipation so i cut down on the fiber and drank juice & ground flax seed.& i take flexeril at night. you all are in my prayers good luck. hopefull you will ask the Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Side effects of taking too much plaquenil Plaquenil Uses, Dosage & Side Effects -, Rx Side Effects New Plaquenil Guidelines and More - American. Can plaquenil cause inflammation in my respiratory systemDifference chloroquine bafilomycin a1Plaquenil for lupus review alkalinePrasco labs hydroxychloroquinePlaquenil pill dosage Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Long-Term Side Effects of Plaquenil for Rheumatoid.. Bad Side Effects of Plaquenil -. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Plaquenil has replaced chloroquine because it produces less retinal side effects. Taking Plaquenil for more than 5 years and if the total amount taken by the patient reaches more than 1000 g may put the patient at risk for the toxicity 1. Patient characteristics. When cut, too much of the drug can be released at once and cause a reaction or side effects. When prescribed 300 mg. daily, you should alternate one tablet one day with two the next. I've been on Plaquenil for almost four years now and it's helped me a lot. Tell your doctor right away if you have any serious side effects, including arm/leg/back pain, slow heartbeat, symptoms of heart failure such as shortness of breath, swelling ankles/feet.