An audit of 100 patients seen at any of nine Canadian rheumatology clinics during early 2016 showed that 30% of patients were not on appropriate weight-based hydroxychloroquine dosages, and 13% of patients on the drug had not received a baseline retinal assessment during their first year of treatment, “We are significantly below the standard of care for appropriately dosing and screening” patients treated with hydroxychloroquine (Plaquenil), concluded Dr. Koppikar, an internal medicine physician at Queens University in Kingston, Ont. Chloroquine treatment of cells Sjogren's i can't tolerate plaquenil Regarding the dosing of hydroxychloroquine, we advocate the use of a weight based dosing regimen with a cap at 400 mg per day, except in the case of renal insufficiency, when the dose should be reduced to 200 mg per day and for those on dialysis, who should take their hydroxychloroquine, 200 mg three times per week. Dosing. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Using this formula, the dosage for a 150-pound person would be 443 mg/day, as one kilogram equals 2.2 pounds. Because HCQ is formulated as a 200 mg tablet, many people taking it for lupus will take two pills per day. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Although his study did not examine reasons for the compliance shortfall, Dr. HCQ comes only as 200-mg tablets, and prescribing intermediate dosages can be a challenge (although veteran clinicians know that a safe and easy way to dial down a dosage is to have the patient periodically skip a dose). In a second recently reported study, researchers from the Chicago area documented that roughly half of the 554 rheumatology patients on hydroxychloroquine (HCQ) in a regional health system and seen by an ophthalmologist during 2009-2016 received an excessive dosage of the drug (). Hydroxychloroquine renal dosing Plaquenil Oral Uses, Side Effects, Interactions, Pictures., Drug spotlight on hydroxychloroquine Lupus Foundation of America Hydroxychloroquine lupus treatmentCanc plaquenil give you ulcersPlaquenil long term use side effects200 mg of hydroxychloroquine daily Usual Adult Dose for Rheumatoid Arthritis. -Initial dose 400 to 600 mg 310 to 465 mg base orally once a day to optimum response usually 4 to 12 weeks -Maintenance dose 200 to 400 mg 155 to 310 mg base orally once a day Dose adjustment The dose may need to be reduced temporarily if adverse side effects occur; Hydroxychloroquine Dosage Guide with Precautions -. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America. Patients with renal insufficiency were dosed at 200 mg daily, and those on hemodialysis received 200 mg after their sessions. In their analysis, Hopkins researchers calculated that ideal and actual body weight dosing yielded statistically equivalent hydroxychloroquine blood levels. “This was reassuring. Of note, however, although the average daily dose of hydroxychloroquine was comparable for those who had not developed renal damage than for those who had developed it, the maximum average dose was higher in the first than in the second group, again supporting its protective role. Some limitations of our study are worth noting.