Hydroxychloroquine renal dosing

Discussion in 'Pharmacy Northwest Canada' started by Fonoman, 23-Feb-2020.

  1. yokomal Moderator

    Hydroxychloroquine renal dosing


    An audit of 100 patients seen at any of nine Canadian rheumatology clinics during early 2016 showed that 30% of patients were not on appropriate weight-based hydroxychloroquine dosages, and 13% of patients on the drug had not received a baseline retinal assessment during their first year of treatment, “We are significantly below the standard of care for appropriately dosing and screening” patients treated with hydroxychloroquine (Plaquenil), concluded Dr. Koppikar, an internal medicine physician at Queens University in Kingston, Ont.

    Chloroquine treatment of cells Sjogren's i can't tolerate plaquenil

    Regarding the dosing of hydroxychloroquine, we advocate the use of a weight based dosing regimen with a cap at 400 mg per day, except in the case of renal insufficiency, when the dose should be reduced to 200 mg per day and for those on dialysis, who should take their hydroxychloroquine, 200 mg three times per week. Dosing. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Using this formula, the dosage for a 150-pound person would be 443 mg/day, as one kilogram equals 2.2 pounds. Because HCQ is formulated as a 200 mg tablet, many people taking it for lupus will take two pills per day. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.

    Although his study did not examine reasons for the compliance shortfall, Dr. HCQ comes only as 200-mg tablets, and prescribing intermediate dosages can be a challenge (although veteran clinicians know that a safe and easy way to dial down a dosage is to have the patient periodically skip a dose). In a second recently reported study, researchers from the Chicago area documented that roughly half of the 554 rheumatology patients on hydroxychloroquine (HCQ) in a regional health system and seen by an ophthalmologist during 2009-2016 received an excessive dosage of the drug ().

    Hydroxychloroquine renal dosing

    Plaquenil Oral Uses, Side Effects, Interactions, Pictures., Drug spotlight on hydroxychloroquine Lupus Foundation of America

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  6. Usual Adult Dose for Rheumatoid Arthritis. -Initial dose 400 to 600 mg 310 to 465 mg base orally once a day to optimum response usually 4 to 12 weeks -Maintenance dose 200 to 400 mg 155 to 310 mg base orally once a day Dose adjustment The dose may need to be reduced temporarily if adverse side effects occur;

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    Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America. Patients with renal insufficiency were dosed at 200 mg daily, and those on hemodialysis received 200 mg after their sessions. In their analysis, Hopkins researchers calculated that ideal and actual body weight dosing yielded statistically equivalent hydroxychloroquine blood levels. “This was reassuring. Of note, however, although the average daily dose of hydroxychloroquine was comparable for those who had not developed renal damage than for those who had developed it, the maximum average dose was higher in the first than in the second group, again supporting its protective role. Some limitations of our study are worth noting.

     
  7. prmy Moderator

    Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite. Antimalarial drugs in pregnancy a review. Hydroxychloroquine MotherToBaby I’m Pregnant What Pain Meds Can I Take?
     
  8. jayhafling New Member

    Description: An exception occurred while processing your request. New Plaquenil Guidelines Interstitial lung disease - Symptoms and causes - Mayo Clinic Plaquenil Toxicity - Sarcoidosis - Inspire
     
  9. Anderson New Member

    Methotrexate and its benefit for Sjögren’s patients Methotrexate is an extremely important therapy for Sjögren’s and many other rheumatic and inflammatory. Follow us on our journey to change the face of Sjogren’s. Methotrexate and its benefit for Sjögren’s patients. Posted on. NSAIDs, low doses of steroids and Plaquenil hydroxychloroquine are often managed with methotrexate.

    Rheumatoid Arthritis Treatment Options Johns Hopkins.