Prophylaxis for international travel to chloroquine resistant area

Discussion in 'Pharmacy Northwest Canada' started by Android87, 29-Feb-2020.

  1. Mareen Guest

    Prophylaxis for international travel to chloroquine resistant area


    Updated information reflecting changes since publication can be found in the online version of this book (gov/yellowbook) and on the CDC Travelers’ Health website (gov/travel). The information was accurate at the time of publication; however, this information is subject to change at any time as a result of changes in disease transmission or, in the case of YF, changing country entry requirements.

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    Apr 15, 2002 Chloroquine is the drug of choice for people who travel to these areas; however, resistance to chloroquine is now widespread in all areas of the world where malaria is endemic, but it is still an effective choice for prophylaxis in travelers to Mexico, the Caribbean, Central America, Argentina. Feb 24, 2020 Recommended by CDC and others as a drug of choice for prophylaxis in those traveling to areas where chloroquine-resistant P. falciparum malaria has been reported; 115 121 134 also can be used for prophylaxis in those traveling to areas where chloroquine-resistant P. falciparum has not been reported. 115 121 134 Your doctor will want you to start taking this medicine 1 to 2 weeks before you travel to an area where there is a chance of getting malaria. This will help you to see how you react to the medicine. Also, it will allow time for your doctor to change to another medicine if you have a reaction to this medicine.

    Arguin (Malaria) The following pages present country-specific information on yellow fever (YF) vaccine require­ments and recommendations (Table 2-06) and malaria transmission information and prophy­laxis recommendations. Country-specific maps of malaria transmission areas, country-specific maps depicting yellow fever vaccine recommen­dations, and a reference map of China are included to aid in interpreting the information.

    Prophylaxis for international travel to chloroquine resistant area

    When should travelers begin malaria prophylaxis? MDedge., Atovaquone and Proguanil Hydrochloride Monograph for.

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  5. An alternative to chloroquine for prophylaxis only in areas with chloroquine-sensitive malaria 310 mg base 400 mg salt orally, once/week 5 mg/kg base 6.5 mg/kg salt orally, once/week, up to a maximum adult dose of 310 mg base Begin 1–2 weeks before travel to malarious areas.

    • Malaria - Chapter 4 - 2020 Yellow Book Travelers' Health..
    • Chloroquine Oral Route Proper Use - Mayo Clinic.
    • Recommendations for the Prevention of Malaria Among Travelers.

    Long-Term Malaria Prophylaxis for Travelers. Both mefloquine and doxycycline are appropriate prophylactic drugs for chloroquine-resistant. those who travel frequently to and from endemic. In contrast to the pretreatment times for all other malarial prophylaxes, the generally accepted pretreatment time for mefloquine is 1 to 2 weeks before entering a risk area. However, this may still be inadequate due to the drug’s long half-life, which results in a long delay in reaching therapeutic blood levels. Such prophylaxis should be sought, ideally, several months before departure. Resurgences of malaria are occurring in areas where the disease had previously been controlled, making prophylaxis essential for travel to endemic areas. Other mild disorders may be treated with medication appropriate to the type of travel and area.

     
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