Dermatologists need to be aware that it is possible for patients to easily purchase isotretinoin online without a prescription, without physician oversight, and without adhering to the FDA-mandated i Pledge compliance program. A female patient recently presented to my office for a case of dry lips and acne flare-ups. We were discussing her therapy and within the first minute or two of the discussion, she said, “I’ve been on this pill I’ve been getting online called Accutane and I’m on my third month.” Upon inquiring about where she’d gotten the drug and who her dermatologist was, she said she didn’t have a prescription and had been getting it online, and that the process was simple. 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