Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Differential diagnosis for plaquenil retinopathy Complete list of side effects of plaquenil Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine What medicines target same receptors as plaquenil Hey Carol. My lupus symptoms began with CNS issues including the jerking, but with plaquenil etc, the jerking subsided for many months. Lately every time I flare I become a jerk. I especially notice it when my body is at rest. Some part muscle/tendon must be in motion constantly and it's jerking, not twitching. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil twitching Sjogren's tingling, muscle twitching, does anyone get it., Hydroxychloroquine Plaquenil Lamictal and plaquenil Eye twitching in case of eye spasm. The 3 most common types of eyelid spasms are eyelid twitch, essential blepharospasm, and hemifacial spasm. Eyelid Twitch Generally, a small unilateral spasm of your lower or upper eyelid, or sometimes both eyelids, is common, of no concern, and typically deals within a couple of days. Eyelid Spasms Causes, Symptoms and Treatment. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Leading Causes Of Muscle Twitches And Spasms - HealthPrep. I also experienced annoying, chronic eye twitching many years ago when placed on Effexor XR for about one year. As soon as I stopped the Effexor XR, the eye twitching resolved. Along with the current problem of the right eye twitch while on the Plaquenil, I have been experiencing one vaginal infection after the next, after the next. Simple motor tics may include movements such as eye -blinking, nose-twitching, head-jerking, or shoulder -shrugging. Complex motor tics consist of a series of movements performed in the same order. For instance a person might reach out and touch something repeatedly or kick out with one leg and then the other. The Risk of Retinal Toxicity with Plaquenil. Posted on Fri, Aug 29, 2014 Tweet; Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus erythematosus SLE and other inflammatory and autoimmune diseases.